Rahul Sharma (Editor)

Premnaspirodiene oxygenase

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EC number
  
1.14.13.121

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

Premnaspirodiene oxygenase (EC 1.14.13.121, HPO, Hyoscymus muticus premnaspirodiene oxygenase) is an enzyme with systematic name (-)-vetispiradiene,NADPH:oxygen 2alpha-oxidoreductase. This enzyme catalyses the following chemical reaction

(-)-vetispiradiene + 2 NADPH + 2 H+ + 2 O2 ⇌ solavetivone + 2 NADP+ + 3 H2O (overall reaction)(1a) (-)-vetispiradiene + NADPH + H+ + O2 ⇌ solavetivol + NADP+ + H2O(1b) solavetivol + NADPH + H+ + O2 ⇌ solavetivone + NADP+ + 2 H2O

Premnaspirodiene oxygenase heme-thiolate protein (P-450).

References

Premnaspirodiene oxygenase Wikipedia
(Text) CC BY-SA


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