Predojević is a Serbo-Croatian surname, derived from the Old Slavic name Predoje (from Predislav). It comes from the katun Vlachs in medieval Bosnia. It may refer to:
Ilija Predojević (fl. 1378), nobleman
Gazi Hasan-paša Predojević (d. 1593), Bosnian Ottoman military commander
Maxim Predojević, Bishop of Križevci 1630–1642
Gabrijel Predojević, Bishop of Križevci 1642–1644
Vasilije Predojević, Bishop of Križevci 1644–1648
Vladimir Predojević, Serbian icon painter (St. Michael's Cathedral)
Draženko Predojević, Serbian acquitted war crime indictee
Srđan Predojević, Serbian TV-host (RTV Pink)
Nemanja Predojević, Serbian TV actor (Potpisani)
Borki Predojević (b. 1987), Bosnian chess Grandmaster
