Precorrin 6A reductase

In enzymology, a precorrin-6A reductase (EC 1.3.1.54) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are precorrin 6B and NADP⁺, whereas its 3 products are precorrin 6A, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is precorrin-6B:NADP+ oxidoreductase. Other names in common use include precorrin-6X reductase, and precorrin-6Y:NADP+ oxidoreductase. This enzyme participates in porphyrin and chlorophyll metabolism.