Precorrin 4 C11 methyltransferase

In enzymology, a precorrin-4 C11-methyltransferase (EC 2.1.1.133) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + precorrin-4 ⇌ S-adenosyl-L-homocysteine + precorrin-5

Thus, the two substrates of this enzyme are S-adenosyl methionine and precorrin 4, whereas its two products are S-adenosylhomocysteine and precorrin 5.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase. Other names in common use include precorrin-3 methylase, and CobM. This enzyme participates in porphyrin and chlorophyll metabolism.