Girish Mahajan (Editor)

Precorrin 2 C20 methyltransferase

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EC number
  
2.1.1.130

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

In enzymology, a precorrin-2 C20-methyltransferase (EC 2.1.1.130) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + precorrin-2 S-adenosyl-L-homocysteine + precorrin-3A

Thus, the two substrates of this enzyme are S-adenosyl methionine and precorrin 2, whereas its two products are S-adenosylhomocysteine and precorrin 3A.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase. This enzyme participates in porphyrin and chlorophyll metabolism.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2E0K and 2E0N.

References

Precorrin-2 C20-methyltransferase Wikipedia