Pothier is a French surname. Notable people with the surname include:
Robert Joseph Pothier (1699 – 1772), French jurist and writer on contract law
Toussaint Pothier (1771 – 1845) Canadian businessman, seigneur and political figure in Lower Canada.
Dom Joseph Pothier, O.S.B. (1835–1923), French prelate, liturgist and scholar of Gregorian chant
Aram Jules Pothier (1854 –1928) was an American banker and Governor of Rhode Island
Albert A. Pothier (fl.1890's) Nova Scotia Assemblyman
Lucien Pothier (1883–1957), French racing cyclist
Hector J. Pothier (1891 – 1976) Canadian physician and Assemblyman in Nova Scotia
Lucien Pothier (wrestler) (born 1894, date of death unknown), Belgian Olympic wrestler
Hector Pothier (born 1954), Canadian football player
Brian Pothier (born 1977),American NHL ice hockey player.
Eric Pothier (born 1979), Canadian luger
