Popescu (Francisized as Popesco) is a family name very common in Romania (derived from popă, meaning priest). Used on its own, it may refer to:
Adrian Popescu, football (soccer) player
Alexe Popescu, chemist
Augustin Popescu, comic book artist
Bogdan Popescu, basketball player
Călin Popescu-Tăriceanu, politician
Cezar Popescu, rugby union player
Constantin Popescu, World War II flying ace
Constantin Popescu, politician
Constantin Popescu, filmmaker
Corneliu M. Popescu, poet and translator
Cosmin Popescu (environmental scientist) Timișoara
Cristian Popescu (poet), poet
Cristian Dumitru Popescu, Romanian-American mathematician
Cristian Tudor Popescu, journalist and writer
Cristian Popescu Piedone, politician
Dan Popescu, comic book artist
Dan Ioan Popescu, politician
Dan Mircea Popescu, politician
Daniel Popescu, footballer
David Popescu, soldier and politician
David Popescu, perennial candidate in Canadian elections
Dimitrie Popescu, rower
Dorin Popescu, mathematician
Dorin Gheorghe Popescu, archaeologist and historian
Dumitru Popescu, politician
Dumitru I. Popescu, general and politician
Dumitru Radu Popescu, writer and communist activist
Elena Liliana Popescu, poet and translator
Elvira Popescu, actress
Eugen-Cristian Popescu, high jumper
Florin Popescu, canoer
Gabriel Popescu, football (soccer) player
Gheorghe Cartianu-Popescu, engineer
Gheorghe Popescu, football (soccer) player
Gheorghe Popescu-Ciocănel, World War II flying ace
Ilie Daniel Popescu, artistic gymnast
Ioan-Ioviţ Popescu, physicist
Ion Popescu-Gopo, animator and cartoonist
Ion Popescu-Pasărea, musician, musicologist, and schoolteacher
Ion Popescu-Puţuri, communist activist and historian
Ion Popescu-Voiteşti, geologist
Ionuţ Popescu, politician
Iulia Popescu, actress
J. David Popescu, Canadian politician
Liliana Popescu, middle distance runner
Lucian Popescu, boxer
Maria Popesco, victim of an alleged Swiss judicial error
Marin Popescu-Spineni, geographer
Marioara Popescu, rower
Mihai Popescu, actor
Mitică Popescu, actor
N. D. Popescu-Popnedea, writer
Nicolae Popescu, mathematician
Radu Popescu, Wallachian chronicler
Răsvan Popescu, journalist
Rodica Popescu Bitănescu, actress
Smaranda Popescu, actress
Sorin Popescu, mathematician
Spiridon Popescu, writer
Ştefan Popescu, painter
Stela Popescu, actress
Stelian Popescu, journalist and fascist activist
Tudor Popescu, writer
Valerian C. Popescu, stomatologist
Vasile Popescu, painter