Pompeo is both a masculine Italian given name and a surname, derived from the Roman "Pompeius". Notable people with the name include:
Given name:
Pompeo Aldrovandi (1668–1752), Italian Cardinal of the Roman Catholic Church
Pompeo Aldrovandini (1677–1735), Italian painter of the Baroque period
Pompeo Batoni (1708–1787), Italian painter
Pompeo Cannicciari (1670–1744), Italian composer
Pompeo Colonna (1479–1532), Italian Cardinal, politician and condottiero
Pompeo Coppini (1870–1957), Italian sculptor who emigrated to the United States
Pompeo D'Ambrosio (1917–1998), Italian who became a Venezuelan businessman
Pompeo Ghitti (1631–1703), Italian painter of the Baroque period
Pompeo Landulfo (1515–1590), Italian painter of the Renaissance period
Pompeo Marchesi (born 1790), Lombard sculptor of the neoclassical school
Pompeo Posar (1921–2004), Playboy magazine staff photographer
Pompeo Targone, Italian military engineer in the service of Ambrose Spinola
Surname:
Ellen Pompeo (born 1969), American actress, played Meredith Grey on the ABC medical drama Grey's Anatomy
Mike Pompeo (born 1963), Director of Central Intelligence Agency, former U.S. Representative for Kansas's 4th congressional district