In Greek mythology, the name Polymele or Polymela may refer to:
Daughter of Peleus and one of the possible mothers of Patroclus by Menoetius, the other two being Sthenele and Periopis; some refer to her as "Philomela".
Daughter of Phylas and wife of Echecles. She was loved by Hermes, who spotted her while she was performing a ritual dance in honor of Artemis, and had by him a son Eudorus.
Daughter of Aeolus. When Odysseus visited their island, he fell in love with her and lay with her secretly. Soon after the guest's departure, Aeolus discovered his daughter crying over some spoils from Troy which Odysseus had given to her as presents. Outraged, he was about to exact vengeance upon Polymele, but his son Diores, who was in love with his own sister, intervened and implored Aeolus to marry her to him, to which Aeolus consented.
Mother of Calchas by Thestor.
Daughter of Autolycus and one of the possible mothers of Jason.
