EC number 4.2.2.3 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9024-15-1 BRENDA BRENDA entry KEGG KEGG entry | |
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In enzymology, a poly(beta-D-mannuronate) lyase (EC 4.2.2.3) is an enzyme that catalyzes the chemical reaction
Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is poly(beta-D-1,4-mannuronide) lyase. Other names in common use include alginate lyase I, alginate lyase, alginase I, alginase II, and alginase. This enzyme participates in fructose and mannose metabolism.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1HV6, 1J1T, and 2CWS.
References
Poly(beta-D-mannuronate) lyase Wikipedia(Text) CC BY-SA