EC number 3.1.1.75 BRENDA BRENDA entry KEGG KEGG entry | IntEnz IntEnz view ExPASy NiceZyme view MetaCyc | |
In enzymology, a poly(3-hydroxybutyrate) depolymerase (EC 3.1.1.75) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are [[poly[(R)-3-hydroxybutanoate]n]] and H2O, whereas its two products are [[poly[(R)-3-hydroxybutanoate]n-x]] and [[poly[(R)-3-hydroxybutanoate]x; x]].
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is poly[(R)-3-hydroxybutanoate] hydrolase. Other names in common use include PHB depolymerase, poly(3HB) depolymerase, poly[(R)-hydroxyalkanoic acid] depolymerase, poly(HA) depolymerase, poly(HASCL) depolymerase, and poly[(R)-3-hydroxybutyrate] hydrolase.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2D80 and 2D81.