Supriya Ghosh (Editor)

Pirarubicin

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ATC code
  
L01DB08 (WHO)

PubChem CID
  
3033521

Molar mass
  
627.63 g/mol

CAS Number
  
72496-41-4

Formula
  
C32H37NO12

Pirarubicin

AHFS/Drugs.com
  
International Drug Names

Legal status
  
In general: ℞ (Prescription only)

Synonyms
  
(9S)-7-[(2R,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yl]oxyoxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

Pirarubicin meaning


Pirarubicin (INN) is an anthracycline drug. An analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.

References

Pirarubicin Wikipedia