Pincus or Pinkus is a surname of Jewish origin, derived from the given name Pinkus, which in turn originates with the Biblical Hebrew male personal name Pinechas or Phinehas. The name may refer to:
Albert Pinkus (1903–1984), American chess player
Anne Pincus (born 1961), Australian artist
Ed Pincus (1938–2013), American filmmaker
David Pincus (1926–2011), American art collector
Gregory Goodwin Pincus (1903–1967), American biologist
Harold Alan Pincus (born 1951), American psychiatrist
Irving Pincus (1914–1984), American writer
Jeff Pinkus (born 1967), American musician
Lionel Pincus (1931–2009), American businessman
Mark Pincus (born 1966), American businessman
Robert Pincus-Witten (born 1935), American art critic and historian
Shimshon Dovid Pincus (1944–2001), Israeli rabbi
Steven Pincus (born 1962), American historian
Walter Pincus (born 1932), American journalist
Zachary Pincus-Roth (born 1979), American writer
Robert Pincus MD (born 1952) American otolaryngologist
Gabriel A Pincus (born 1983) Investor and president of GA Pincus funds
Hannah M Pincus (born 1989) American Special Assistant to Treasury Secretary Lew