Puneet Varma (Editor)

Piminodine

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Covid-19
ATC code  none
PubChem CID  21950
UNII  3IIX447HWS
CAS Number  13495-09-5
ChemSpider  20628
Molar mass  366.497 g/mol
Piminodine
Legal status  AU: S9 (Prohibited) CA: Schedule I DE: Anlage I (Controlled) US: Schedule II

Piminodine (Alvodine) is an opioid analgesic that is an analogue of pethidine (meperidine). It was used in medicine briefly during the 1960s and 1970s, but has largely fallen out of clinical use. It was used particularly for obstetric analgesia and in dental procedures and, like pethidine, could be combined with hydroxyzine to intensify the effects. The duration of action is 2 to 4 hours and 7.5 to 10 mg via the subcutaneous route is the most common starting dose, being equal to 80 to 100 mg of pethidine, 40 to 60 mg of alphaprodine and 10 mg of morphine. Oral formulations were also available.

Piminodine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

Piminodine is currently a Schedule II controlled substance in the United States. It has a DEA ACSCN of 9730 and in 2013 the aggregate annual manufacturing quota for the US was zero.

References

Piminodine Wikipedia


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