Pimeloyl CoA dehydrogenase

In enzymology, a pimeloyl-CoA dehydrogenase (EC 1.3.1.62) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are pimeloyl-CoA and NAD⁺, whereas its 3 products are 6-carboxyhex-2-enoyl-CoA, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is pimeloyl-CoA:NAD+ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.