Pickles is a surname. Notable people with the surname include:
Albert Pickles (1877–1958), English association football player and managerChristina Pickles (born 1935), British born American actressChristopher Pickles (born 1966), English cricketerDavid Pickles (born 1935), English cricketerEric Pickles (born 1952), British conservative politicianJames Pickles (1925–2010), controversial British judgeLewis Pickles (born 1932), English cricketerVivian Pickles (born 1931), English actressWilfred Pickles (1904–1978), English actor and radio presenterWilliam Pickles (1885–1962), English epidemiologist