Neha Patil (Editor)

Phosphosulfolactate synthase

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EC number
  
4.4.1.19

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

In enzymology, a phosphosulfolactate synthase (EC 4.4.1.19) is an enzyme that catalyzes the chemical reaction

(2R)-2-O-phospho-3-sulfolactate phosphoenolpyruvate + hydrogen sulfite

Hence, this enzyme has one substrate, (2R)-2-O-phospho-3-sulfolactate, and two products, phosphoenolpyruvate and hydrogen sulfite.

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is (2R)-2-O-phospho-3-sulfolactate hydrogen-sulfite-lyase (phosphoenolpyruvate-forming). Other names in common use include (2R)-phospho-3-sulfolactate synthase, and (2R)-O-phospho-3-sulfolactate sulfo-lyase.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1U83.

References

Phosphosulfolactate synthase Wikipedia