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Phosphopantetheine

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Formula
  
C11H23N2O7PS

Molar mass
  
358.349 g/mol

Phosphopantetheine The Phosphopantetheine Cofactor Of Acyl Carrier Pr Cheggcom

Phosphopantetheine, also known as 4'-Phosphopantetheine, is an essential prosthetic group of acyl carrier protein (ACP) and peptidyl carrier proteins (PCP) and aryl carrier proteins (ArCP) derived from Coenzyme A. It is also present in formyltetrahydrofolate dehydrogenase.

Phosphopantetheine The Phosphopantetheine Cofactor Of Acyl Carrier Pr Cheggcom

Functions

Phosphopantetheine fulfills two demands.

Phosphopantetheine The Phosphopantetheine Cofactor Of Acyl Carrier Pr Cheggcom

  • First, the intermediates remain covalently linked to the synthases (or synthetases) in an energy-rich thiol ester linkage.
  • Second, the flexibility and length of phosphopantetheine chain (approximately 2 nm) allows the covalently tethered intermediates to have access to spatially distinct enzyme active sites.

    • Phosphopantetheine pubsrscorgservicesimagesRSCpubsePlatformSer

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    References

    Phosphopantetheine Wikipedia
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