Species Human Entrez 8612 | Human Mouse Ensembl ENSG00000141934 | |
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Aliases PLPP2, LPP2, PAP-2c, PAP2-g, PPAP2C, Phosphatidic acid phosphatase 2c, phospholipid phosphatase 2 External IDs MGI: 1354945 HomoloGene: 2752 GeneCards: PLPP2 | ||
Lipid phosphate phosphohydrolase 2 is an enzyme that in humans is encoded by the PPAP2C gene.
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
References
Phosphatidic acid phosphatase 2c Wikipedia(Text) CC BY-SA