Neha Patil (Editor)

Phenylserine aldolase

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EC number
  
4.1.2.26

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37290-60-1

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a phenylserine aldolase (EC 4.1.2.26) is an enzyme that catalyzes the chemical reaction

L-threo-3-phenylserine glycine + benzaldehyde

Hence, this enzyme has one substrate, L-threo-3-phenylserine, and two products, glycine and benzaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming). This enzyme is also called L-threo-3-phenylserine benzaldehyde-lyase. It employs one cofactor, pyridoxal phosphate.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1V72.

References

Phenylserine aldolase Wikipedia