Suvarna Garge (Editor)

Phenotypic switching

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Phenotypic switching is switching between multiple cellular morphologies.

Phenotypic switching in Candida albicans changes the cells from white to opaque in need for sexual mating.

A second example occurs in Melanoma, where malignantly transformed pigment cells switch back-and-forth between phenotypes of proliferation and invasion in response to changing microenvironments, driving metastatic progression.

References

Phenotypic switching Wikipedia