Pharmahuasca is a pharmaceutical version of the entheogenic brew ayahuasca. Traditional ayahuasca is made by brewing the MAOI-containing Banisteriopsis caapi vine with a DMT-containing plant, such as Psychotria viridis. Pharmahuasca refers to a similar combination that uses a pharmaceutical MAOI instead of a plant.
For pharmahuasca, 50 mg N,N-DMT and 100 mg harmaline is usually the recommended dosage per person. However, combinations of 50 mg harmaline, 50 mg harmine, and 50 mg, N,N-DMT have been tested with success. As a rule, the fewer the β-carbolines, the less the nausea; the more DMT, the more spectacular the visions. The constituents are put into separate gelatin capsules. The capsules with harmaline/harmine is swallowed first and the capsule containing the DMT is taken 15 to 20 minutes later. The purely synthetic MAO inhibitor Marplan is suitable in place of harmaline and harmine, although caution should be taken as this is an irreversible MAOI.