Pfaff is a surname. Notable people with the surname include:
Alfred Pfaff, German football player
Anita Bose Pfaff, economist
Chris Pfaff, American television actor
Debby Pfaff, reality show personality
Dieter Pfaff (1947–2013), German actor
Eva Pfaff, German tennis player
Ferenc Pfaff, Hungarian architect
Georg Michael Pfaff, German manufacturer of sewing machines (See the article in German Wikipedia)
Jean-Marie Pfaff, Belgian football player
Johann Friedrich Pfaff, German mathematician
Concepts named after him include the Pfaffian, Pfaffian functions, and the Pfaff problem
29491 Pfaff, a main-belt asteroid named in his honour
Kristen Pfaff, American musician
Lyndsey Pfaff, reality show personality
Petra Pfaff, East German hurdler
William Pfaff, American author
Judy Pfaff, artist