Pettis is a surname. Notable people with the name include:
Anthony Pettis, American mixed martial artist
Austin Pettis, American football wide receiver
Billy James Pettis, American mathematician
Bre Pettis, American entrepreneur, video blogger and multi-artist
Bridget Pettis, American basketball player
Garret Pettis, American soccer player
Gary Pettis, American baseball player
Jerry Pettis, American politician
Jill Pettis, New Zealand politician
Madison Pettis, American actress and model
Mark Pettis, American politician from Wisconsin
Pierce Pettis, American singer-songwriter
Sergio Pettis, American mixed martial artist, brother of Anthony
Shirley Neil Pettis, U.S. Representative from California, wife of Jerry
Solomon Newton Pettis, American politician
Spencer Darwin Pettis, U.S. Representative from Missouri
Will Pettis, Arena football wide receiver, defensive back
