Perkin is a surname. Notable people with the surname include:
Arthur George Perkin (1861–1937), English chemist, son of William Henry Perkin
Graham Perkin (1929–1975), Australian journalist and newspaper editor
Richard Scott Perkin (1906–1969), American entrepreneur
William Henry Perkin (1838–1907), English chemist
William Henry Perkin, Jr. (1860–1929), English organic chemist, son of William Henry Perkin