Periportal space

The periportal space, or periportal space of Mall, is a space between the stroma of the portal canal and the outermost hepatocytes in the hepatic lobule, and is thought to be one of the sites where lymph originates in the liver.

Fluid (residual blood plasma) that is not taken up by hepatocytes drains into the periportal space, and is taken up by the lymphatic vessels that accompany the other portal triad constituents.