Peploe is a surname which is shared by:
Samuel Peploe (bishop) (1667–1752), Bishop of ChesterSamuel Peploe (1871–1935), Scottish Post-Impressionist painterDorothy Emily Peploe, the married name of Scottish author D. E. Stevenson (1892–1973)Clare Peploe (born 1942), director, screenwriter and wife of Bernardo BertolucciMark Peploe (born 1943), screenwriter and film directorChris Peploe (born 1981), English cricketerGeorge Peploe, husband of actress Violet CarsonEdward Peploe Smith (1803–1847), son of George Smith (1765–1836), British Member of Parliament, banker and director of the East India CompanyDaniel Peploe, High Sheriff of Herefordshire 1846Daniel Peploe, Member of Parliament for Herefordshire 1874–1880