Pentalenene oxygenase

Pentalenene oxygenase (EC 1.14.13.133, PtlI) is an enzyme with systematic name pentalenene,NADPH:oxygen 13-oxidoreductase. This enzyme catalyses the following chemical reaction

pentalenene + 2 NADPH + 2 H⁺ + 2 O₂ ⇌ pentalen-13-al + 2 NADP⁺ + 3 H₂O (overall reaction)(1a) pentalenene + NADPH + H⁺ + O₂ ⇌ pentalen-13-ol + NADP⁺ + H₂O(1b) pentalen-13-ol + NADPH + H⁺ + O₂ ⇌ pentalen-13-al + NADP⁺ + 2 H₂O

Pentalenene oxygenase is a heme-thiolate protein (P-450).