In the geometry of hyperbolic 4-space, the pentagrammic-order 600-cell honeycomb is one of four regular star-honeycombs. With Schläfli symbol {3,3,5,5/2}, it has five 600-cells around each face in a pentagrammic arrangement. It is dual to the small stellated 120-cell honeycomb. It can be considered the higher-dimensional analogue of the 4-dimensional icosahedral 120-cell and the 3-dimensional great dodecahedron. It is related to the order-5 icosahedral 120-cell honeycomb and great 120-cell honeycomb: the icosahedral 120-cells and great 120-cells in each honeycomb are replaced by the 600-cells that are their convex hulls, thus forming the pentagrammic-order 600-cell honeycomb.
This honeycomb can also be constructed by taking the order-5 5-cell honeycomb and replacing clusters of 600 5-cells meeting at a vertex with 600-cells. Each 5-cell belongs to five such clusters, and thus the pentagrammic-order 600-cell honeycomb has density 5.