Pentachlorophenol monooxygenase

Pentachlorophenol monooxygenase (EC 1.14.13.50, pentachlorophenol dechlorinase, pentachlorophenol dehalogenase, pentachlorophenol 4-monooxygenase, PCP hydroxylase, pentachlorophenol hydroxylase, PcpB, PCB 4-monooxygenase, PCB4MO) is an enzyme with systematic name pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating). This enzyme catalyses the following chemical reaction

(1) pentachlorophenol + 2 NADPH + H⁺ + O2 ⇌ 2,3,5,6-tetrachlorohydroquinone + 2 NADP⁺ + chloride + H₂O(2) 2,3,5,6-tetrachlorophenol + NADPH + H⁺ + O2 ⇌ 2,3,5,6-tetrachlorohydroquinone + NADP⁺ + H₂O

Pentachlorophenol monooxygenase is a flavoprotein (FAD).