Harman Patil (Editor)

Penitrem A

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Formula
  
C37H44ClNO6

Penitrem A httpsuploadwikimediaorgwikipediacommons77

Penitrem A (tremortin) is a fungal neurotoxin found on ryegrass. It is produced by certain species of Aspergillus, Claviceps, and Penicillium. It inhibits potassium channels in smooth muscles. The maxi-channels targeted have their highest density in the cerebellar Purkinje cells.

It causes a stagger in horses and cattle.

Stages of toxicity

  • Acute tremor
  • Chronic ataxia
  • Little recovery
  • References

    Penitrem A Wikipedia