Penfold is an English-language surname. Notable people with the surname include:
Adrian Penfold (born 1952), British planning expert
Bernard Penfold (1916–2015), British Army officer
Christopher Penfold, British writer and producer in radio and television
Christopher Rawson Penfold (born 1811), Viticulturist and entrepreneur of South Australia's wine industry
David Penfold (born 1964), field hockey player from New Zealand
Frank C. Penfold (1849–1921), American artist and teacher
Jodie Penfold, British television presenter
John Penfold (1828–1909), British surveyor and architect
John Penfold (priest) (1864–1922), British Anglican priest
Liz Penfold (born 1947), Australian politician
Mary Penfold (died 1895), Viticulturist and entrepreneur of South Australia's wine industry
Mark Penfold (born 1956), English professional footballer
Merimeri Penfold (1920–2014), New Zealand Māori educator
Peter Penfold (born 1944), British diplomat
Robert Penfold (born 1951), Foreign Correspondent for Australia's Nine News
