Payan or Payán is a surname. Notable people with the surname include:
Saralah Payan (born 1983), MIS manager in education of iran
Ana Rosa Payán, Mexican right-wing politician, Director of the National System for Integral Family Development
Claude-François de Payan (1766–1794), political figure of the French Revolution
Eliseo Payán (1825–1895), Colombian lawyer, politician, and military officer
Estevan Payan (born 1982), American professional mixed martial artist
Eugene Payan (1888–1971), Canadian professional ice hockey player
Ferdinand Payan, French bicyclist of the early 20th century
Funda Payan (born 1997), Turkish women's football midfielder
Ilka Tanya Payán (1943–1996), Dominican-born actress and attorney, later an HIV/AIDS activist in the United States
Joseph-François de Payan (1759–1852), political figure during the French Revolution, brother of Claude-François de Payan
Sébastien Payan (born 1986), rugby league player for the Toulouse Olympique team in the Co-operative Championship
Alan Payan Pryce-Jones TD (1908–2000), British book critic, author, journalist and Liberal Party politician
Payan Rafat (born 1970), retired Iranian footballer and current coach