Paolucci, also spelled Paulucci, and historically scarcely as Paoluzzi, Pauluzzi and Paluzzi is an Italian surname deriving from the given name Paolo (Paulus). It may refer to:
Adriano Paolucci (b. 1979), Italian male volleyball player
Andrea Paolucci (b. 1986), Italian footballer.
Fabrizio Paolucci (1651–1726), Catholic cardinal
Fabrizio Paolucci (1726–1810)
Federico Paulucci (b. 1990), Argentinian footballer
Gianfranco Paolucci (b. 1934), Italian fencer
Jeno Paulucci (1918-2011), American businessman and entrepreneur
Loris Paoluzzi (b. 1974), Italian retired male hammer thrower
Luciana Paluzzi (b. 1937), Italian actress
Marianna Paulucci (1835–1919), Italian naturalist
Mario Paolucci (1941-2008), Argentinian film actor
Michele Paolucci (b. 1986), Italian footballer
Pauluccio Paulucci-Alberoni (fl. 1670-1676), Catholic cardinal and coadjutor to Pope Clement X
Philip Osipovich Paulucci (1779–1849), Italian marquis, served in the Russian Army as adjutant general
