Pancreatic stellate cell

Pancreatic stellate cells (PaSCs or PSCs) are myofibroblast-like cells that can switch between the quiescent and activated phenotypes, like hepatic stellate cells. PaSCs reside in exocrine areas of the pancreas. When activated, PaSCs migrate to the injured location, and participate in tissue repair activities, secreting ECM components. PaSCs may play a role in the pathogenesis of pancreatitis and pancreatic cancer.