EC number 3.1.2.22 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 150605-49-5 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a palmitoyl[protein] hydrolase (EC 3.1.2.22) is an enzyme that catalyzes the chemical reaction
palmitoyl[protein] + H2OThus, the two substrates of this enzyme are [[palmitoyl[protein]]] and H2O, whereas its two products are palmitate and protein.
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is palmitoyl[protein] hydrolase. Other names in common use include palmitoyl-protein thioesterase, and palmitoyl-(protein) hydrolase. This enzyme participates in fatty acid elongation in mitochondria.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1EH5, 1EI9, 1EXW, and 1PJA.
References
Palmitoyl(protein) hydrolase Wikipedia(Text) CC BY-SA