Species Human Entrez 5831 | Human Mouse Ensembl ENSG00000183010 | |
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Aliases PYCR1, ARCL2B, ARCL3B, P5C, P5CR, PIG45, PP222, PRO3, PYCR, pyrroline-5-carboxylate reductase 1 External IDs MGI: 2384795 HomoloGene: 56002 GeneCards: PYCR1 | ||
Pyrroline-5-carboxylate reductase 1, mitochondrial is an enzyme that in humans is encoded by the PYCR1 gene.
This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.
References
PYCR1 Wikipedia(Text) CC BY-SA