Entrez 5780 | Ensembl ENSG00000169410 | |
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Aliases PTPN9, MEG2, PTPMEG2, protein tyrosine phosphatase, non-receptor type 9 External IDs MGI: 1928376 HomoloGene: 2121 GeneCards: PTPN9 | ||
Tyrosine-protein phosphatase non-receptor type 9 is an enzyme that in humans is encoded by the PTPN9 gene.
Function
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by poly-phosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
References
PTPN9 Wikipedia(Text) CC BY-SA