Species Human Entrez 51450 | Human Mouse Ensembl ENSG00000167157 | |
Aliases PRRX2, PMX2, PRX2, paired related homeobox 2 External IDs MGI: 98218 HomoloGene: 7524 GeneCards: PRRX2 |
Paired mesoderm homeobox protein 2 is a protein that in humans is encoded by the PRRX2 gene.
Function
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation.
References
PRRX2 Wikipedia(Text) CC BY-SA