Entrez 23082 | Ensembl ENSG00000148840 | |
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Aliases PPRC1, PRC, peroxisome proliferator-activated receptor gamma, coactivator-related 1 External IDs MGI: 2385096 HomoloGene: 9006 GeneCards: PPRC1 |
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 is a protein that in humans is encoded by the PPRC1 gene.
The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1). This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals.
Interactions
PPRC1 has been shown to interact with USF2.
References
PPRC1 Wikipedia(Text) CC BY-SA