Entrez 5496 | Ensembl ENSG00000115241 | |
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Aliases PPM1G, PP2CG, PP2CGAMMA, PPP2CG, protein phosphatase, Mg2+/Mn2+ dependent 1G External IDs MGI: 106065 HomoloGene: 31106 GeneCards: PPM1G |
Protein phosphatase 1G is an enzyme that in humans is encoded by the PPM1G gene.
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
References
PPM1G Wikipedia(Text) CC BY-SA