PNU 181731

PNU-181731 is a drug which acts as an agonist at serotonin 5-HT₂ receptors, with strongest binding affinity for the 5-HT_2C subtype at 4.8nM, and weaker 5-HT_2A affinity of 18nM. It has anxiolytic effects in animal studies with around one tenth the potency of alprazolam and no significant ataxia or other side effects noted.