Entrez 5332 | Ensembl ENSG00000101333 | |
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Aliases PLCB4, ARCND2, PI-PLC, phospholipase C beta 4 External IDs MGI: 107464 HomoloGene: 8471 GeneCards: PLCB4 | ||
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 is an enzyme that in humans is encoded by the PLCB4 gene.
Function
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Two transcript variants encoding different isoforms have been found for this gene.
References
PLCB4 Wikipedia(Text) CC BY-SA