Rahul Sharma (Editor)

PLCB3

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Aliases
  
PLCB3

Human
  
Ensembl
  
ENSG00000149782

Species
  
Entrez
  
5331

PLCB3

External IDs
  
MGI: 104778 HomoloGene: 47960 GeneCards: PLCB3

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 is an enzyme that in humans is encoded by the PLCB3 gene.

The gene codes for the enzyme phospholipase C β3. The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11, as well as G-beta gamma subunits.

Interactions

PLCB3 has been shown to interact with Sodium-hydrogen exchange regulatory cofactor 2.

References

PLCB3 Wikipedia


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