Species Human Entrez 80055 | Human Mouse Ensembl ENSG00000197121 | |
Aliases PGAP1, Bst1, ISPD3024, MRT42, SPG67, post-GPI attachment to proteins 1 External IDs MGI: 2443342 HomoloGene: 41605 GeneCards: PGAP1 | ||
Post-GPI attachment to proteins 1 is a protein that in humans is encoded by the PGAP1 gene.
Function
The protein encoded by this gene functions early in the glycosylphosphatidylinositol (GPI) biosynthetic pathway, catalyzing the inositol deacylation of GPI. The encoded protein is required for the production of GPI that can attach to proteins, and this may be an important factor in the transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi. Defects in this gene are a cause of mental retardation, autosomal recessive 42.
References
PGAP1 Wikipedia(Text) CC BY-SA