Entrez 5217 | Ensembl ENSG00000070087 | |
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Aliases PFN2, D3S1319E, PFL, profilin 2 External IDs MGI: 97550 HomoloGene: 1974 GeneCards: PFN2 |
Profilin-2 is a protein that in humans is encoded by the PFN2 gene.
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Interactions
PFN2 has been shown to interact with ROCK1, Vasodilator-stimulated phosphoprotein, CCDC113 and FMNL1.
References
PFN2 Wikipedia(Text) CC BY-SA