Routes of
administration Oral CAS Number 1202647-54-8 ChemSpider 26610764 Molar mass 372.524 g/mol | ATC code None PubChem CID 44599828 Formula C21H28N2O2S Route Oral administration | |
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PF-4455242 is a selective, short-acting (non-"inactivating") antagonist of the κ-opioid receptor. Discovered by Pfizer in 2009, it was pursued in a phase I clinical trial for the treatment of bipolar disorder, and was also investigated as a treatment for depression and substance abuse. However, development was stopped in September 2010 due to toxicology findings in animals that had been exposed to the drug for three months.
References
PF-4455242 Wikipedia(Text) CC BY-SA