Entrez 10611 | Ensembl ENSG00000163110 | |
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Aliases PDLIM5, ENH, ENH1, LIM, L9, PDZ and LIM domain 5 External IDs MGI: 1927489 HomoloGene: 21289 GeneCards: PDLIM5 |
PDZ and LIM domain protein 5 is a protein that in humans is encoded by the PDLIM5 gene.
The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.
Interactions
PDLIM5 has been shown to interact with PRKCB1.