Supriya Ghosh (Editor)

PDE9A

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Species
  
Human

Entrez
  
5152

Human
  
Mouse

Ensembl
  
ENSG00000160191

PDE9A

Aliases
  
PDE9A, HSPDE9A2, phosphodiesterase 9A

External IDs
  
MGI: 1277179 HomoloGene: 113565 GeneCards: PDE9A

High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A is an enzyme that in humans is encoded by the PDE9A gene.

The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene.

Inhibitors

  • BAY 73-6691
  • PF-04447943
  • References

    PDE9A Wikipedia