External IDs GeneCards: PCGEM1 Human Mouse Ensembl ENSG00000227418 | Species Human Entrez 64002 | |
 | ||
Aliases PCGEM1, LINC00071, NCRNA00071, PCAT9, prostate-specific transcript (non-protein coding) | ||
Prostate-specific transcript 1 (non-protein coding), also known as PCGEM1, is a long non-coding RNA gene. In humans, it is located on chromosome 2q32. It is over-expressed in prostate cancer. In a study of prostate tumours from 88 men, levels of PCGEM1 were found to be higher in prostate cancer cells in African-American men than in Caucasian-American men. The mortality rate of prostate cancer is highest in African-American men.
PCGEM1 inhibits doxorubicin-induced apoptosis of cells, via delayed induction of p53 and p21.
References
PCGEM1 Wikipedia(Text) CC BY-SA